millions treated for hypothyroidism at risk for lung cancer

SayerJiis founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, SteeringCommittee Memberof the Global Non-GMO Foundation. Data sources: The Medline and Cochrane Library electronic databases . Untreated hypothyroidism increases morbidity and mortality. They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. When a high-risk patient presents with one or more lung nodules, the path ahead and next steps seems obvious. Clin Cancer Res 2011, 30:77. Millions of people who were not only wrongly diagnosed with 'cancers' and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. I think there is always a lot of confusion with cause and cure. Sin un requerimiento, el cumplimiento voluntario por parte de tu Proveedor de servicios de Internet, o los registros adicionales de un tercero, la informacin almacenada o recuperada slo para este propsito no se puede utilizar para identificarte. They compared sale of, "However, the impression we get from our experience, Health, Studies, Supps & Pharmaceuticals. Correlation is not causation. LifeGivingStore.comRed Light Therapy - Hydrogen Water Generators - Cascara Sagrada - Vitamins, Minerals & Amino Acid Supplements - Cocoa Products - Handcrafted Soaps - Grass Fed Organs & Glandulars - Nano Soma. This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic 'self-fulfilling prophecy' if you will. J Clin Endocrinol Metab. [9] Otto T, Fandrey J: Thyroid hormone induces hypoxia-inducible factor 1 gene expression through thyroid hormone receptor /retinoid x receptor -dependent activation of hepatic leukemia factor. A couple of caveats to note in this study: The authors found a statistical correlation between the increase in sales of the thyroid medicine Synthroid, and an increase in lung cancer in Italy. This relatively symptom-free reservoir of hypothyroid cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. However, they pointed out that the opposite was recently described, and that "hypothyroidism reduces theaggressiveness of some cancers because of the presence of thyroid hormone receptors oncancer cells, and spontaneous hypothyroidism may delay onset or reduce aggressiveness ofcancers."[1]. 2 Hypothyroidism is the most common type of thyroid disorder, and women's risk of hypothyroidism is five to eight times higher than that of . Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: The authors also cite animal experimental research which has shown that T4 increases the oxidative stress[6] and spontaneous pulmonary metastases in mice. In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. Cancer-related fatigue (CRF) is common in lung cancer survivors and can occur at any point in the care continuum. Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. The study looked at the prevalence of breast, colorectal, gastric and lung cancer in 18 Italian Regions during 2010 and correlated this data with sales of LT4 in 2009, focusing on women aged 30-84. Other factors that can trigger thyroid problems include: autoimmune diseases like Hashimoto's or Graves' disease; thyroid surgery; radiation treatments to the neck or upper chest; and certain medications, including interferon alpha and interleukin-2 cancer medications, amiodarone . [4] Ratcliffe JG, Stack BH, Burt RW, Radcliffe WA, Spilg WG, Cuthbert J, Kennedy RS: Thyroid function in lung cancer. PMID 11836274. I don't think so. Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. rocket fuel, pesticides, fluoride, which induce low thyroid function. Is so taking anti oxidants might be an idea. weight loss, anorexia). " The reality is that most cases of hypothyroidism today are diagnosed in populations who are experiencing a combination of basic nutritional deficiencies and chemical exposures, or who are simply going through a temporary down-cycle in thyroid function following a natural change, such as the natural postpartum drop that occurs in women after giving birth. Overtreatment, of course, is the hallmark danger of overdiagnosis. The reality is that most cases of hypothyroidism today are diagnosed in populations who are experiencing a combination of basic nutritional deficiencies and chemical exposures, or who are simply going through a temporary down-cycle in thyroid function following a natural change, such as the natural postpartum drop that occurs in women after giving birth. Scan this QR code to download the app now. "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)", International Journal of Human Nutrition and Functional Medicine, Osteoporosis Is Scurvy of the Bone, Not Calcium Deficiency, 6 Bodily Tissues That Can Be Regenerated Through Nutrition, 7 Simple Ways to Unclog Your Arteries Naturally, Herbal Cream Clears 87.7% of HPV Cases Naturally, How WHOLE Turmeric Heals the Damaged Brain. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. For more, visitGreenMedInfo.comand Facebook.com/GreenMedInfo, or sign up forGreenMedInfos free e-Newsletter. El almacenamiento o acceso tcnico es necesario para crear perfiles de usuario para enviar publicidad, o para rastrear al usuario en una web o en varias web con fines de marketing similares. The authors of the study pointed out that levothyroxine (T4) treatment can lead to medication-induced (iatrogenic) thyroid over-activity (hyperthyroidism) and oxidative stress that can lead to a significant patient discomfort. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Or, if fluoride, mercury, or any number of xenobiotic chemicals in the environment requiring selenium-dependent glutathione-mediated detoxification is causing the low thyroid, why call chemical poisoning hypothyroidism? Increased sensitivity to cold. [12] Cesarone MR, Belcaro G, Nicolaides AN, Incandela L, De Sanctis MT, Barsotti A: San Valentino epidemiologic project. I cried with joy when I found out there was something really wrong with me. If I can help someone, fine. Diagnosed 1/12 with lung cancer out of the blue. An Italian study published in the journalReproductive Biology and Endocrinology,titled Levothyroxine and lung cancer in females: the importance of oxidative stress, has raised a concerning possibility: levothyroxine (T4), one of the worlds most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). Biomedicine today is awash in controversy associated with the overdiagnosis and overtreatment of asymptomatic populations. In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. Not what people like me are saying. There is also the very real possibility that T4 will not only not properly interact with thyroxine cellular receptors, but will block out what remaining natural levothyroxine the thyroid is still producing (and whose conformational state is far more health-promoting), essentially acting as an endocrine disrupter at the very moment that it is acting as intended as a 'TSH suppressor.' J Exp Biol 2010, 213:28992911. Due to excessive bot signups along with nefarious actors we are limiting forum registration. Or, if fluoride, mercury, or any number of xenobiotic chemicals in the environment requiring selenium-dependent glutathione-mediated detoxification is causing the "low thyroid," why call chemical poisoning "hypothyroidism"? "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)". There are several books out there written about the topic. The American Lung Association connects patients, families, friends and caregivers for support and inspiration as they face lung cancer. A place for patients and relatives. is the fiec part of the evangelical alliance; townhomes in avalon park; 8 ft windmill parts; why is my cash and sweep vehicle negative; nordstrom rack return policy worn shoes Eventually, the decline in thyroid hormone production can result in any of the following: Fatigue and sluggishness. In my view the paper isn't worth the pixels used to display it on a screen. As I am the caregiver for my dad who has Stage IV lung Cancer, I hope more research can be done on this topic soon. Angiology 2000, 51:S65S68. Article published in Wakeup-World.Com. [10] Hofer T, Desbaillets I, Hpfl G, Wenger RH, Gassmann M: Characterization of HIFD-1 alpha overexpressing Hela cells and implication for gene therapy. 1 The number of individuals with thyroid disorders is expected to continue to grow, having reached approximately 750 million globally in 2012. Asesora y Consultora Web3 para empresas. Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. Endocrinology 2008, 149:22412250. Symptoms. If it's high, the test is done again, along with a blood test for the thyroid hormone T-4. Those with the greatest risk of developing thyroid disorders are women who have a family history of the disease. Join the forum, it's quick and easy . Just go on one of the thyroid sites and read the stories. I have been reading Izabella Wentz. weight loss, anorexia) was made many years ago together with an over production of both T4 and T3. A total of 425 inpatients with malignant tumors were treated with ICIs at PUMCH during the study period. En 3 minutos recibirs en tu email COMPLETAMENTE GRATIS todo lo que necesitas para aumentar las ventas de tu empresa. [2], The observation that patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. Just another excuse for keeping us on doses that are too low. Is Drug-Based Medicine a Form of Human Sacrifice? Modern Medicine, Part I: How Healing Illness Becam Is your body getting too acidic? [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. Study: Millions Treated for Hypothyroidism At Risk of Lung Cancer. Patients with incomplete information (n = 127), preexisting hypothyroidism or levothyroxine replacement before initiation of ICI therapy (n = 11), or other factors known to contribute to thyroid dysfunction after immunotherapy (n = 17) were excluded (Fig. [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism. The Remarkable Heart-Friendy Properties of Avocados. Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new 'disease' case the patient is converted into a lifelong customer. [3], An old clinical observation on the relationship between lung cancer and thyroid function reported that patients were characterized by a low concentration of T3 and an increased T4/T3 ratio due to a decrease of 5-monodeiodination (DI). Capmatinib (Tabrecta) is the first FDA-approved MET-targeting medication for treating metastatic NSCLC. Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. I honestly do not know. She wrote about a product called Thyrtophin PMG. [5] Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5' deiodinase in lung cancer with peripheral lung tissues. Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. 2004 Jun;9(2):157-79. Acta Endocrinol 1988, 118:460464. I'm not saying that there Is no link between Synthroid and lung cancer. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. Endocrinology 1985, 117:12011208. It does not necessarily imply one thing caused the other. Thyroid disease is a major public health concern worldwide. [2] Meng R, Tang HY, Westfall J, London D, Cao JH, Mousa SA, Luidens M, Hercbergs A, Davis FB, Davis PJ, et al: Crosstalk between integrin v3 and estrogen receptor- is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. Post author By ; Post date jaripeo hillsboro oregon 2021; what task do they have at camp westerbork on millions treated for hypothyroidism at risk for lung cancer on millions treated for hypothyroidism at risk for lung cancer I have no further scientific evidence. I posted it to see what anyone had to add. [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. Post Considering that the population in Italy is about 60 million people and the sales of LT4 in the country in 2010 were 17.69 million boxes (+ 6% Vs 2009), hypothyroidism, which is the main reason for the prescription, should be a real national concern (almost 0.7 boxes/women/year). I have posted the link, so you can see if it has any merit. In the U.S., the overall five-year survival rate for patients diagnosed with lung cancer is 25%, which is a 21% improvement over the . Very interesting article, thank you for sharing. Levothyroxine is a widely prescribed medication for the treatment of an underactive thyroid. [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3'-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. Most of the time, doctors tell patients treated with LT4 that any side effects will be temporary and almost ineluctable, and are usually dealt with through dose reduction. According to data from the National Health and Nutrition Examination Survey, years 1988-1994, [13] while 0.3% of the American population exhibits overt symptoms of hypothyroidism, 14 times more (4.3%) have so-called subclinical hypothyroidism only detected via blood work. It was the therapist that I went to that referred me to a specialist who ran the correct tests. Compression of the trachea, which may be positional, can occur with nodular goiters and thyroid cancer, and the latter can metastasize to the lungs. Marketed as superior to traditional glandular forms extracted from pigs (whose endocrine glands are far more bioidentical than any other animal we know of) due to the dose-to-dose standardization of the so-called active ingredient T4 versus the natural variations in hormone concentrations found in the real thing, which incidentally contains a wide range of additional hormones including T1, T2, T3, all of which are vitally important. Importance: Whether radioactive iodine (RAI) therapy for hyperthyroidism can increase cancer risk remains a controversial issue in medicine and public health. [6] Venditti P, Di Stefano L, Di Meo S: Oxidative stress in cold induced hyperthyroid state. Overtreatment, of course, is the hallmark danger of overdiagnosis. A distorted idea of human nature is sold when people are treated as "the market. Hypothyroidism results from low levels of thyroid hormone with varied etiology and manifestations. Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new disease case the patient is converted into a lifelong customer. Or that it was the many years of not being diagnosed with hypothyroidism, courtesy of daft blood test ranges, before finally tipping a TSH over 5 (or even 10) before treatment is commenced, by which time the damage is done. PMID: 15253676. This discussion has been closed to comments. There is also compelling research indicating that desiccated thyroid extract (Armour thyroid) results in superior clinical outcomes versus the synthetic hormone, especially as concerns improved body weight. ", That study is like a fishing expedition. and our [15] [16]There is also the more logical option of support the bodys thyroid-hormone producing capabilities using the thyroxine precursor L-tyrosine, a basic amino acid with a relatively high margin of safety. You are using an out of date browser. Baked or Fried avocado fries [Vegetarian]. Objectives: To examine site-specific cancer incidence and mortality and to evaluate the radiation dose-response association after RAI treatment for hyperthyroidism. 500+ pages of Natural Medicine Alternatives and Information. The increasingly global medical-industrial complex has begun to co-opt all aspects of the natural human bodily life cycle, and all the organ systems within it, as potential targets of medical surveillance and intervention, not excluding the human thyroid. CRF encompasses physical, emotional, and/or cognitive tiredness; is related to cancer or cancer treatments; and interferes with multiple dimensions of health-related quality of life (1-3).CRF is poorly understood, underrecognized, and undertreated. The first blood test typically done to diagnose hypothyroidism measures the level of thyroid-stimulating hormone (TSH) in the blood. Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low . Researchers are currently studying. I have sent the link that I read today. Physician/Author on Facebook. Unfortunately, it's quite typical. [14] In other words, you can 'normalize' the main clinically measurable parameter associated with 'low thyroid function,' i.e. The authors of the study pointed out that levothyroxine (T4) treatment can lead to medication-induced (iatrogenic) thyroid over-activity (hyperthyroidism) and oxidative stress that can lead to a significant patient discomfort. It may not display this or other websites correctly. In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to replacement therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. I will respond more later onBut I will briefly say I was on Synthyroid from 1993 to 2011. But that's just me. I had doctor after doctor tell me it was in my head or I was menopausal. Even in the mildest form, hypothyroidism affects the heart. ", Cure Alveolar Soft Part Sarcoma International, COMPLETED - Dana Farber Vaccine Clinical Trial (GVAX), Axitinib and Pembrolizumab (Keytruda) in Miami, US, TECENTRIQ (atezolizumab) by Genentech, Treatment of Non-Resectable Primary Tumor, Immune checkpoint inhibitors ICI (PD-1 and PD-L1 targeting drugs), Toxicity, problems and potentiation strategies, Treatment response criteria and evaluation/scanning problems/rare cases, treatment discontinuation/re-treatment, Side effects/complications of the local ablations, High intensity focused ultrasound (HIFU), Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer, http://www.greenmedinfo.com/blog/study- ng-cancers. [14] K A Woeber. Is This the Real Reason You're Exhausted All the T Why An Alkaline Approach Can Successfully Treat Ca We're Losing the War on Cancer- Here's Why. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional. If people do not wish to find out all they can about their disease that is fine too. One of the main drawbacks of administering T4 in isolation is the possibility that it will not convert adequately to T3, and will therefore back up causing excessive T4 activity, i.e. A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). Correlation is NOT causation. Why not simply call it selenium deficiency? With the recent announcement by a National Cancer Institute commissioned expert panel that a variety of so-called 'indolent' neoplasms such as ductal carcinoma in situ (DCIS) and high-grade prostatic intraepithelial neoplasia (HGPIN), formerly understood to be forms of breast and prostate cancers, respectively, should be renamed to reflect their intrinsic benignity, a veritable sea change is occurring within the conventional medical establishment.